{"id":1758,"date":"2022-01-24T12:47:28","date_gmt":"2022-01-24T12:47:28","guid":{"rendered":"https:\/\/akademperiodyka.org.ua\/en\/?p=1758"},"modified":"2025-07-10T08:51:55","modified_gmt":"2025-07-10T08:51:55","slug":"tumor_hypoxia_in_the_clinical_setting","status":"publish","type":"post","link":"https:\/\/akademperiodyka.org.ua\/en\/books\/tumor_hypoxia_in_the_clinical_setting\/","title":{"rendered":"Tumor hypoxia in the clinical setting"},"content":{"rendered":"<div class=\"content\">\n<div class=\"field field-name-field-book-project field-type-taxonomy-term-reference field-label-inline clearfix\">\n<div class=\"field-item even\">Project: Ukrainian scientific book in a foreign language<\/div>\n<\/div>\n<div class=\"field field-name-field-book-editors field-type-name field-label-inline clearfix\">\n<div class=\"field-item even\">Editors: <strong>S. Osinsky, H. Friess, P. Vaupel<\/strong><\/div>\n<\/div>\n<div class=\"field field-name-field-book-year field-type-number-integer field-label-inline clearfix\">\n<div class=\"field-item even\">Year: 2011<\/div>\n<\/div>\n<div class=\"field field-name-field-pages field-type-text field-label-inline clearfix\">\n<div class=\"field-item even\">Pages: 272<\/div>\n<\/div>\n<div class=\"field field-name-field-book-isbn field-type-text field-label-inline clearfix\">\n<div class=\"field-item even\">ISBN: 978-966-360-169-4<\/div>\n<\/div>\n<div class=\"field field-name-field-book-publication-language field-type-taxonomy-term-reference field-label-inline clearfix\">\n<div class=\"field-item even\">Publication Language: English<\/div>\n<\/div>\n<div class=\"field field-name-field-book-publisher field-type-text field-label-inline clearfix\">\n<div class=\"field-item even\">Publisher: PH &#8220;Akademperiodyka&#8221;<\/div>\n<\/div>\n<div class=\"field field-name-field-book-place-published field-type-text field-label-inline clearfix\">\n<div class=\"field-item even\">Place Published: Kyiv<\/div>\n<\/div>\n<div class=\"field field-name-field-book-doi field-type-link-field field-label-inline clearfix\">\n<div class=\"field-item even\">doi: <a href=\"https:\/\/doi.org\/10.15407\/akademperiodyka.169.272\">https:\/\/doi.org\/10.15407\/akademperiodyka.169.272<\/a><\/div>\n<\/div>\n<div class=\"field field-name-field-book-type field-type-taxonomy-term-reference field-label-inline clearfix\">\n<div class=\"field-item even\">Book Type: Monograph<\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<div>\n<hr \/>\n<\/div>\n<div class=\"content\">\n<div class=\"field field-name-body field-type-text-with-summary field-label-hidden\">\n<div class=\"field-items\">\n<div class=\"field-item even\">\n<p class=\"rtejustify\">This monograph considers the data from pathophysiological studies of human tumors, in particular concerning the pathogenesis of tumor hypoxia and the molecular basis of its impact on tumor aggressiveness. Special attention has been paid to the relevance of tumor hypoxia for diagnosis and treatment, as well as for the prognosis of disease outcome. Tumor response to treatment and approaches to enhance its efficacy are considered, with special emphasis on the role played by intratumoral hypoxia. The link between the molecular mechanism of malignant growth and the pathophysiological characteristics of neoplasia is discussed using the example of human tumors.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<hr \/>\n<div class=\"content\">\n<div class=\"field field-name-field-references field-type-text-long field-label-above\">\n<h4 class=\"field-label\">References:<\/h4>\n<\/div>\n<\/div>\n<div><\/div>\n<div class=\"content\">\n<div class=\"field field-name-field-references field-type-text-long field-label-above\">\n<div class=\"field-items\">\n<p class=\"field-item even\">Adams GE (1991) Hypoxia: new mechanisms for old? 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Radiother Oncol 97:172 175<a href=\"https:\/\/doi.org\/10.1016\/j.radonc.2010.05.012\">https:\/\/doi.org\/10.1016\/j.radonc.2010.05.012<\/a><br \/>\nVaupel P, and Mayer A (2007) Hypoxia in cancer: significance and impact on clinical outcome.Cancer Metastasis Rev 26:225 239<a href=\"https:\/\/doi.org\/10.1007\/s10555-007-9055-1\">https:\/\/doi.org\/10.1007\/s10555-007-9055-1<\/a><br \/>\nVaupel P (2008) Hypoxia and aggressive tumor phenotype: Implications for therapy and progno sis. Oncologist 13(suppl. 3):21 26<a href=\"https:\/\/doi.org\/10.1634\/theoncologist.13-S3-21\">https:\/\/doi.org\/10.1634\/theoncologist.13-S3-21<\/a><br \/>\nvon Hoff DD, Stephenson Jr JJ, Rosen P et al. (2010) Pilot study using molecular profiling of patients&#8217; tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol 28:4877 4883<a href=\"https:\/\/doi.org\/10.1200\/JCO.2009.26.5983\">https:\/\/doi.org\/10.1200\/JCO.2009.26.5983<\/a><br \/>\nWinter SC, Buffa FM, Silva P et al. (2007) Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Res 67:3441 3449<a href=\"https:\/\/doi.org\/10.1158\/0008-5472.CAN-06-3322\">https:\/\/doi.org\/10.1158\/0008-5472.CAN-06-3322<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Project: Ukrainian scientific book in a foreign language Editors: S. Osinsky, H. Friess, P. Vaupel Year: 2011 Pages: 272 ISBN: 978-966-360-169-4 Publication Language: English Publisher: PH &#8220;Akademperiodyka&#8221; Place Published: Kyiv doi: https:\/\/doi.org\/10.15407\/akademperiodyka.169.272 Book Type: Monograph This monograph considers the data from pathophysiological studies of human tumors, in particular concerning the pathogenesis of tumor hypoxia and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1759,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,21,24],"tags":[],"class_list":["post-1758","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-books","category-scientific_monographs","category-ukrainian_scientifical_book"],"_links":{"self":[{"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/posts\/1758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/comments?post=1758"}],"version-history":[{"count":4,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/posts\/1758\/revisions"}],"predecessor-version":[{"id":3559,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/posts\/1758\/revisions\/3559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/media\/1759"}],"wp:attachment":[{"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/media?parent=1758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/categories?post=1758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/akademperiodyka.org.ua\/en\/wp-json\/wp\/v2\/tags?post=1758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}